Hif1抗体
http://docs.abcam.com/pdf/protocols/HIF-alpha_EN.pdf Web10 de abr. de 2024 · 总的来说，AMPK和几种Sirtuins的激活或上调有利于健康衰老，预防癌症发生。因此，活化的AMPK磷酸化可以消除参与细胞生长和维持癌细胞干性通路的关键成分，可以构成抗癌药物的潜在靶点。SIRT6是一种促长寿因子，其可通过抑制HIF1和MYC的转录从而抑制肿瘤。
Hif1抗体
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Web8 de fev. de 2008 · We herein report the role of nutrient availability on the regulation of HIF-1. A reduced availability of glucose, not amino acids, results in a decrease of the expression of HIF1-dependent genes and HIF-1 alpha protein in response to hypoxia. HIF-1 alpha mRNA expression was not significantly suppressed and DMOG, an inhibitor for … Web7 de jun. de 2024 · This study not only demonstrated that HIF1α-GPD1 forms a positive feedforward loop inhibiting mitochondrial function and lipid metabolism in ccRCC, but also discovered a new mechanism for the molecular basis of HIF1α to inhibit tumor activity, thus providing novel insights into hypoxia-lipid-mediate …
Web5 de ago. de 2024 · The intracellular calcium-dependent PKCα/mammalian target of the rapamycin (mTOR) signaling pathway triggered by cP1P regulated HIF1α translation via S6K1, which is critical for HIF1 activation. Web抗HIF1A抗体 affinity isolated antibody; Synonyms: Anti- HIF1,Anti- HIF1-ALPHA,Anti- MOP1,Anti- PASD8,Anti-HIF-1alpha; find Sigma-Aldrich-SAB2108753 MSDS, related …
WebNational Center for Biotechnology Information WebHIF1-alpha regulates hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis. Hypoxia which induces p53 protein accumulation, directly interacts with HIF1-alpha and reduces hypoxia-induced expression of HIF1-alpha by promoting MDM2-mediated ubiquitination and proteasomal degradation under hypoxic conditions. ... 定制抗体 ...
WebSummary. HIF1 alpha antibody recognizes HIF1 alpha (HIF1a) protein, which is a subunit of the heterodimeric transcription factor hypoxia …
Web回收的抗体在进行Western实验时至少可以重复使用10次。稀释后的抗体，包括已经使用过的稀释抗体，4℃保存。 2. 回收后重复使用的抗体，使用方法同新鲜稀释的抗体。如果在 … iphone text message dictationWeb抗体 稀释缓冲液 ... hif1 复合体由作为 pas（per、arnt、sim）家族碱性螺旋-环-螺旋蛋白的两个亚基 hif-1α 和 hif-1β 组成 (2)。hif1 调节诸多基因类型转录，这些基因可促进低氧环境 … iphone text message dingWebPolyclonal Antibody for studying HIF1-beta. Cited in 19 publications. Validated for Western Blotting, Immunofluorescence (Immunocytochemistry). Highly specific and rigorously validated in-house, HIF-1β/ARNT Antibody (CST #3718) is ready to ship. iphone text message disappearedWebab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. 1/100 - 1/200. We recommend Goat Anti-Mouse IgG H&L (DyLight ® 488) … iphone text message creatorWeb21 de mar. de 2024 · GeneCards Summary for HIF1A Gene. HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, Multiple, Ollier Type . Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated … iphone text message downloaderWeb(Microbial infection) Upon infection by human coronavirus SARS-CoV-2, is required for induction of glycolysis in monocytes and the consequent pro-inflammatory state (PubMed:32697943). In monocytes, induces expression of ACE2 and cytokines such as IL1B, TNF, IL6, and interferons (PubMed:32697943). Promotes human coronavirus … iphone text message hackingWeb什么是重组抗体，为什么它很重要？ 与传统抗体相比，重组抗体具有几个关键优势。这些包括良好的批次间一致性，持续供应以及对抗体工程的适应性。因此，重组抗体在科学研 … iphone text message forwarding