Hif1a molecular weight
Web3 de out. de 2024 · Disclosed are methods and compositions for treating cardiovascular diseases including cardiomyopathy and heart failure. Particularly disclosed are methods and compositions that utilize or comprise inhibitors of hypoxia-inducible factor (HIF)-2α or agonists/inducers of HIF prolyl hydroxylase domain-2 (PHD2) signaling for treating … Web21 de mar. de 2024 · Size: 669 amino acids Molecular mass: 72433 Da Protein existence level: PE1 Quaternary structure: Isoform 2 interacts (via ODD domain) with VHL (via beta …
Hif1a molecular weight
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WebPHD1 (Egln2), PHD-2 (Egln1), and PHD3 (Egln3) are members of the Egln family of proline hydroxylases. They function as oxygen sensors that catalyze the hydroxylation of HIF on prolines 564 and 402, initiating the first step of HIF degradation through the VHL/ubiquitin pathway (1,2). PHD1 is highly expressed in a wide array of tissues whereas ... WebPredicted molecular weight: 93 kDa. The antibody only works in hypoxic cell and tissue lysates. For Mouse specific Hif-1-alpha rabbit monoclonal ... Sumoylation is enhanced …
Web25 de jun. de 2016 · Although exogenous high molecular weight HA and hypoxia have been individually reported to enhance cartilage matrix metabolism, ... (Rn00564204_m1), VEGF (Rn01511602_m1), and HIF1A (Rn01472831_m1). Each 25 µL reaction mixture contained 2 µL of cDNA (100 ng), and 12.5 µL TaqMan Gene Expression PCR Master … Web9 de out. de 2024 · Post-weaning diarrhea (PWD) is frequently associated with E. coli F18 infections in piglets. However, the underlying molecular mechanism concerning the resistance of E. coli F18 in local weaned piglets in China is not clearly understood. In the present study, by a comparative analysis of the transcriptome, a-1,3-fucosyltransferase …
WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) Research with confidence – consistent and … WebDisclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation …
WebEpididymal fat weight differences between genotypes persisted when epididymal fat was expressed as a percentage of overall body weight (5.3% ± 0.2% in Hif1a F/F mice overall vs. 4.6% ± 0.1% in Hif1a −/− hep mice overall; P = 0.034 for genotype effect determined by using two-way ANOVA).
WebProduct Specific Information. MA1-516 detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody … birchwood 450Web23 de jul. de 2024 · HIF-1α Antibody (28b) is an IgG 1 κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the … birchwood ab for saleWebProtein Mutation Frequency in Cancer. The 'lollipop plot' above illustrates recurrent (observed in 3 or more out of 4440 TCGA tumor samples from 15 cancer types) and therefore potentially oncogenic missense mutations (click on 'Show Cancer Mutations'). dallas shuttle serviceWebHIF1-alpha (HIF1A) is a subunit of HIF1, which is a transcription factor found in mammalian cells cultured under reduced oxygen tension. HIF-1 is a heterodimer consisting of an … birchwood 510 commando 2002WebHIF-2 alpha Antibody (PA1-16510) in ICC/IF. Immunofluorescence analysis of HIF-2 alpha was performed using HepG2 cells treated with CoCl2 (300uM for 16hrs). The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. dallas shrubs for shadeWebHIF1A. Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the HIF1A gene. [5] [6] [7] The Nobel Prize in … dallas shriners hospital for childrenWebHIF1A, HIF1, BHLHE78, MOP1, PASD8, HIF-1A, HIF-1alpha, HIF1-ALPHA, HIF-1-alpha. View additional product information. Experiments from the literature. Loading published … birchwood acura