WebApr 4, 2014 · Significance Analysis of INTeractome (SAINT) is a statistical method for probabilistically scoring protein-protein interaction data from affinity purification-mass … WebJun 25, 2024 · We defined the high-confidence proximity interactome of AURKA by performing significance analysis of interactome (SAINT) analysis, which assigns confidence scores for each protein interaction (Teo et al, 2014). We used a SAINT score cutoff of > 0.95, which yielded 440 proteins as high-confidence AURKA proximity …
Label-free quantitative proteomics and SAINT analysis enable ...
WebThe Interactome -Transcriptome Integration (ITI) algorithm allows the analysis of gene expression data by superimposition of a large scale protein-protein interaction data … WebAbstract. We present 'significance analysis of interactome' (SAINT), a computational tool that assigns confidence scores to protein-protein interaction data generated using affinity … how to spell ty in japanese
SAINTexpress: improvements and additional features in …
WebSupporting: 3, Mentioning: 687 - We present SAINT (Significance Analysis of INTeractome), a computational tool that assigns confidence scores to protein-protein interaction data … Label-free quantification in this work was based on spectral counting. Spectral counts are the sum of every successful instance of sequencing a peptide from a particular protein by mass spectrometry, including redundant spectra. With proper normalization, spectral counts can be used as a quantitative … See more This section describes the generalized statistical modeling framework for the datasets with and without control purifications (Fig. 1a,b). In both cases, the spectral … See more CompPASS7,10 calculates two different scores. First, Z score is constructed by mean centering and scale normalization in the conventional Z statistic, where … See more The source C code and a user manual for the generalized SAINT model described in this work (SAINT 2.0) can be downloaded from http://saint … See more Webanalysis of interaction data from AP-MS experiments using label-free quantification, which we termed significance analysis of inter-actome (SAINT) 8. As PP-NSAF and CompPASS, … rdwl515a2000